What is the Cannabinoid CBDA?
The cannabinoid CBDA is one of the cannabinoids detected in cannabis plants, a diverse plant with many beneficial properties. Since ancient times, several cultures have been using cannabis like other plants. The curiosity about this herb is its recreational or medical use and the fact that it was a propaganda target for about a century. At the same time, the stigma remains despite its legalisation in many parts of the world. What is the compound CBDA, its properties, the benefits to the organism, and what’s new in the research field?
Cannabidiolic acid: Useful information
Cannabidiolic acid CBDA is a cannabinoid found in cannabis/hemp plants, isolated in 1955, while it is the first cannabidiolic acid to be discovered. CBDA is abundant in cannabis strains rich in cannabidiol CBD, mainly in the flower’s trichomes. The CBDA chemical compound derives from cannabigerol acid, CBGA, the precursor of the cannabinoids THCA, CBDA, and CBCA. After CBDa decarboxylation, meaning the sun or heat exposure, we observe the conversion to CBD (Cannabidiol). We can find CBDA in several medical cannabis products, such as capsules, cannabis oil, tinctures, and topical cosmetic products.
What are the CBDA benefits? Which properties does it offer to our Organism?
Cannabidiolic acid has drawn the scientific community’s interest thanks to its beneficial properties offered to the organism. It is prominent for its strong anti-inflammatory and analgesic effects. In contrast with other cannabinoids that interact with the receptors CB1 and CB2, the chemical compound CBDA inhibits the impact of the enzyme COX-2 cyclooxygenase produced after inflammatory stimuli. Studies show that CBDA is a more potent compound than CBD. Similar to the THCA, the only problem is that they are pretty unstable molecules. That means they decompose almost directly once exposed to heat, light, or an extraction method.
Therefore, the latest scientific data show that chemists found innovative CBDA stabilization methods to exploit the potential beneficial properties.
Other studies point out that CBDA is 100 times more potent than CBD because it enhances the serotonin activity in the brain, contributing to better management of emotions, stress, and mood. In addition, the antiseptic cannabidiolic acid effect provides better dental care by preventing disorders such as periodontitis. Finally, there are reports of the beneficial effects, reducing the adverse side effects that may appear due to THC use. That’s why many people consuming THC or HHC prefer to combine it with CBDA and CBD to limit the psychoactive tetrahydrocannabinol effect and remain focused and productive.
CBDA Cannabidiolic acid: Beneficial properties
- Stress relief
Similarities between CBD and CBDA
CBD and CBDA share some similarities mainly because of their beneficial properties. They are two chemical compounds without psychoactive effects. According to scientific data, they are two cannabinoids with strong anti-inflammatory and anti-cancer effects. Also, the research for both molecules reports stress relief, nausea, and vomiting control.
Differences between CBD and CBDA:
The two cannabinoids may share some similarities but also some essential differences. First of all, CBD (Cannabidiol) comes from CBDA, which is its precursor. Cannabidiolic acid is detectable in cannabis plants during their growth and blooming stage. On the contrary, CBD results from CBDA exposure to heat or sun. It is important to note that CBD is a more stable molecule than CBDA. Not to exclude that cannabidiolic acid interacts with the serotonin receptors while CBD interacts with the pain receptors TRPV1.
CBDA: research news
Studies concerning the CBDA effect are in progress. There is already scientific data about its beneficial properties, which increase constantly. Recent research published in the scientific magazine International Journal of Molecular Sciences reports the metabolic cannabidiolic acid efficiency. Both cannabidiolic acid CBDA and cannabidiol CBD contribute to better metabolic activity, while they can be helpful for obesity treatment (due to genes or diet).
A study refers to the anti-convulsant effect of CBDA cannabidiolic acid that may benefit children with Dravet syndrome. In this case, the children have seizures because of the fever, while CBDA inhibits pentylenetetrazole action, a substance responsible for these seizures. Other scientific data indicate that CBDA blocks breast cancer from spreading to different cells. Even about coronavirus SARS-CoV-2, there is evidence showing that a vaccine combination with CBDA and CBGA may limit the growth and progress of the virus.
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Research conducted by Ontario University reports that the combination between CBDA and CBD interacts with serotonin 5-HT1A receptors inhibiting nausea caused by the chemotherapy toxins. It is worth underlying the effective cannabidiolic acid function in anticipatory vomiting, which manifests before the chemotherapy and has no medical cure
CBD-a side effects:
Generally speaking, there are no references to cannabidiolic acid side- effects. Therefore, if the product in use contains other cannabinoids or is consumed with other medical drugs, then there may appear some side effects, which disappear either by stopping the product or reducing the percentage.
Potential side effects:
- Low pressure
- Mood swings
Cannabis and cannabidiolic acid CBDA have many prominent beneficial properties enhancing and protecting the organism. Knowledge and prudence can be essential allies when using herbs, especially for disorders or diseases. We always remember that if we follow a medical prescription, we use herbs after communicating with the physician.